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Roundup

Shoulder & Elbow


X-ref X-ref For other Roundups in this issue that cross-reference with Shoulder & Elbow see: Research Roundup 3.

Reverse shoulder arthroplasty: the key is in the greater tuberosity

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This study further highlights the increasing use of reverse total shoulder arthroplasty (rTSA) for complex fractures of the proximal humerus, which was featured in a paper discussed in the last edition of 360.1 This multicentre retrospective study from Zürich (Switzerland) reports the use of rTSA for the more complex head-splitting three- and four-part proximal humeral fractures.2 The authors were able to gather together a series of 51 patients with a mean age of 77 years who were analysed at a mean of three years following acute reverse total shoulder arthroplasty (RSA). Outcomes were assessed using the Constant score and the subjective shoulder value (SSV), both administered at a single follow-up point with patients achieving, on average, 86% of the shoulder function on the other side. A total of 92% of patients rated their management as excellent or good, with overall satisfaction levels high at 93%. Although no intra-operative complications were recorded, of the original 73 patients, four underwent revision surgeries: one periprosthetic humeral fracture, one post-operative haematoma and two infections. An inferior outcome was associated with secondary displacement of the greater tuberosity (GT) when compared with those with a GT that was radiographically united. The authors concluded that rTSA is a sound treatment modality for these difficult and challenging cases, while also suggesting that revision surgery may be indicated for secondary displacement of the GT, although this statement is made without a comparison. This study is one of the largest in the literature reporting on this topic for managing acute complex proximal humeral fractures in elderly patients, where the indication for the reverse implant could be on the rise; utilisation certainly is.

Shoulder arthroplasty may improve the driving performance of patients

It must be one of the most common questions asked by a peri-operative patient: When can I get back to driving? Despite this, there is very little detail available to inform these decisions, with advice routinely given with caution and a lack of data! This elegant study from New York, New York (USA)3 caught our eye at 360 HQ as it addresses this simple question. The investigators used a driving simulator to assess 30 patients, all of whom underwent shoulder arthroplasty surgery (20 anatomic and ten reverse). Patients were assessed pre-operatively and at two, six and 12 weeks post-operatively by analysing a variety of characteristics including total number of collisions and off-road excursions, as well as VAS pain score and the Shoulder Pain and Disability Index (SPADI). Despite the mean number of collisions increasing at week two, as would be expected, driving performance returned to pre-operative levels by six weeks and patients performed better than pre-operatively at 12 weeks post-surgery! Multivariate analysis found that poorer VAS pain scores, increasing age and less driving experience were predictive of a poorer driving performance. The authors concluded that clinicians can suggest a six- to 12-week window post-surgery that can be used for a gradual return to driving, with this being closer to 12 weeks for older patients or in those with less driving experience or higher pain levels. These findings are consistent with a recent paper reporting on driving performance post-arthroscopic shoulder surgery,4 which reported impaired driving performance for a minimum of six weeks post-surgery and a return to normal driving by 12 weeks.

The debate regarding early fixation of acute clavicle fractures continues

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It seems seldom that a major orthopaedic trauma conference goes by without the presentation of another well performed randomised controlled trial comparing non-operative and operative management for acute displaced mid-shaft fractures of the clavicle. Despite some excellent prospective trials and subsequent meta-analyses, the debate continues.5,6 The clavicle is perhaps the one clinical problem that won’t be resolved with randomised trials alone. This large study from Los Angeles, California (USA) using the American College of Surgeons’ National Surgical Quality Improvement Program database compared registry data from a total of 1215 patients who underwent open reduction internal fixation (ORIF) for either an acute mid-shaft clavicle fracture (n = 1006) or a clavicle mid-shaft nonunion (n = 209).7 The primary outcome measure in this study was the 30-day complication rate. The authors reported an increased rate of complications following nonunion surgery (5.26% vs 2.28%) and they subsequently undertook a multivariate analysis in order to establish the predictors for complications. The authors established that there was a two-fold increased risk of all complications in patients with a nonunion, with a three-fold increased risk of wound complications. Interestingly, the authors conclude that these findings should be considered when making definitive management decisions for patients with these injuries. However, given that it has been shown that 6.2 patients would need to undergo surgery to prevent one nonunion, others have suggested that more work is required to identify fractures at risk of nonunion and it is these patients who would be best considered for early surgery.8

Surgery is successful for refractory medial epicondylitis in the longer term

The role of surgery for medial and lateral epicondylitis of the elbow continues to be debated, as does pretty much every other aspect of management. This confusion is likely to be due in part to the heterogeneous nature of some of the series which have been reported, and the natural relapsing remitting history of the condition, making firm conclusions difficult to draw. Most surgeons would, however, agree that surgery may be of benefit when it is reserved for refractory cases. In this single-centre single-surgeon retrospective case series from Gyeonggi (South Korea) the authors report the outcomes of 55 patients treated with 63 cases of medial epicondylitis.9 All patients underwent non-operative interventions prior to consideration for surgery, including treatment for a minimum of one year with at least two steroid injections (a mean of five). At an average follow-up of seven years following surgery, the authors report a significant improvement in the mean visual analogue scale score, grip strength, Mayo Elbow Performance score and the Disabilities of the Arm, Shoulder and Hand score. The post-operative recovery was substantial, with the time to return to work just shy of three months and return to exercise at around five months. The overall reported success rate was 93%, with the Nirschl and Pettrone grades rated 43% as excellent and 51% as good. There was a single case of heterotrophic ossification. This study provides good long-term results supporting the use of surgery for refractory cases of medial epicondylitis of the elbow. We would suggest, here at 360, that this study highlights the importance of emphasising to patients the possibility of a prolonged recovery period10 after such surgery, with patients requiring an average of almost three months off work.

Further evidence to suggest corticosteroid injections are not beneficial in the management of tennis elbow

There is now a strong body of evidence to suggest that corticosteroid injections are not beneficial in the long- or short-term management of enthesopathy of the extensor carpi radialis brevis, otherwise known as ‘tennis elbow’. This large meta-analysis from a team in Boston, Massachusetts (USA) included seven randomised controlled trials (RCTs) identified following a thorough search of the indexed literature.11 All seven included trials compared the effect of corticosteroid injection with a placebo injection on the symptoms of tennis elbow. The authors reported no difference in outcomes between steroid and placebo in terms of pain at three and six months following injection. However, they did report marginal but significantly reduced pain levels at one month post-injection. Grip strength and the Disabilities of the Arm, Shoulder and Hand scores were comparable at all of the time points analysed. Given these findings, the authors concluded that steroid injections for tennis elbow are ‘neither meaningfully palliative nor disease modifying’. This adds further weight against the use of steroid injection for this common condition, with an additional study from this group suggesting that the use of steroids was associated with an increased rate of surgery for the condition.12

Muscle atrophy and fatty infiltration in rotator cuff tears: can surgery stop muscular degenerative changes?

If a rotator cuff tear is left untreated, the natural progression is the secondary development of dysfunction of the cuff musculature, usually the supraspinatus muscle. This is part of the development of a ‘cuff tear arthropathy’. Subsequent management of cuff tear arthropathy is complex, with poor functional outcomes and development of secondary arthroses in the joint, although recently reverse total shoulder arthroplasty has been introduced. The question of course has always been: how does the pathophysiology relate to surgical intervention? Is the die cast at the time of injury? Surgeons from Rome (Italy) have reported their study of 41 patients, all with an MRI-proven rotator cuff tear.13 Although the study was retrospective, the authors were able to identify two subgroups: those who had undergone rotator cuff repairs and those who had not. Outcomes were assessed using a range of shoulder outcome measures and an interval MRI scan at 50 months following diagnosis. The authors established that there were better results in terms of fatty infiltration of the muscle belly in the operative group with no progression of fatty changes, while the non-operative group had significant increases in tendon retraction and tear size. Although this doesn’t establish causation, it does provide some evidence to suggest that tendon repair is able to prevent secondary muscle degeneration.

Anterior plating stronger in the clavicle?

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Historically, clavicle fractures have been plated with a superior approach. Though sigmoid-shaped, the flat surface of the superior aspect of the clavicle allows for easy application of the plate without multiplanar contouring. There is, however, an incidence of metalwork failure. Some fracture patterns are less amenable to superior plate placement; following failure of fixation the best surgical fixation option may be an anterior plate. These authors from Baltimore, Maryland (USA) explore the benefits or otherwise of anterior plate placement in lateral clavicle fractures.14 They designed a cadaveric study that tests the hypothesis that reorientation of the plates to move the screw line away from the axis of the deforming forces would improve the biomechanical strength of the construct. The authors used six pairs of fresh frozen cadavers and undertook standardised osteotomies with superior and anterior plating, prior to mounting them on an Instron machine and loading with 375 N at 1 Hz for 2000 cycles. Following this, sequential loads to failure were tested. There were significant differences in all measures of biomechanical stability, with the most marked difference being in load to failure (587 N vs 375 N) in favour of anterior plating. The authors found that anteriorly plated distal third clavicle fractures have superior strength and durability when compared with fractures plated superiorly in a cadaver model. Clearly there are some limitations to this study. There are few clinical studies, however, from which to base treatment decisions, and their findings are important.

Optimising treatment in olecranon bursitis

As a mostly non-operative diagnosis, olecranon bursitis has been somewhat neglected on the research front over the past decade, with little progress made in treatment despite the comparative frequency of presentation. We were delighted to see this randomised controlled trial from Seoul (South Korea), testing three treatments: compression bandaging and NSAIDs versus steroid injections versus aspiration.15 They report the outcomes of 133 patients randomised to one or other treatment and reported at four weeks’ follow-up. Outcomes were assessed as resolution at four weeks and median time to resolution. Sadly this study did not detect any differences between the three interventions, although the study was only powered to detect a 30% difference. The authors sensibly suggest that this study should be regarded as a pilot, and a large study capable of detecting a greater difference should be undertaken.

References

1 Rosas S , LawTY, KurowickiJ, et al.. Trends in surgical management of proximal humeral fractures in the Medicare population: a nationwide study of records from 2009 to 2012. J Shoulder Elbow Surg2016;25:608-613. Google Scholar

2 Grubhofer F , WieserK, MeyerDC, et al.. Reverse total shoulder arthroplasty for acute head-splitting, 3- and 4-part fractures of the proximal humerus in the elderly. J Shoulder Elbow Surg2016;25:1690-1698.CrossrefPubMed Google Scholar

3 Hasan S , McGeeA, WeinbergM, et al.. Change in driving performance following arthroscopic shoulder surgery. Int J Sports Med2016;37:748-753.CrossrefPubMed Google Scholar

4 Hasan S , McGeeA, GarofoloG, et al.. Changes in driving performance following shoulder arthroplasty. J Bone Joint Surg [Am]2016;98-A:1471-1477.CrossrefPubMed Google Scholar

5 McKee RC , WhelanDB, SchemitschEH, McKeeMD. Operative versus nonoperative care of displaced midshaft clavicular fractures: a meta-analysis of randomized clinical trials. J Bone Joint Surg [Am]2012;94-A:675-684.CrossrefPubMed Google Scholar

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7 Robinson CM , GoudieEB, MurrayIR, et al.. Open reduction and plate fixation versus nonoperative treatment for displaced midshaft clavicular fractures: a multicenter, randomized, controlled trial. J Bone Joint Surg [Am]2013;95-A:1576-1584.CrossrefPubMed Google Scholar

8 McKnight B , HeckmannN, HillJR, et al.. Surgical management of midshaft clavicle nonunions is associated with a higher rate of short-term complications compared with acute fractures. J Shoulder Elbow Surg2016;25:1412-1417.CrossrefPubMed Google Scholar

9 Amin NH , KumarNS, SchickendantzMS. Medial epicondylitis: evaluation and management. J Am Acad Orthop Surg2015;23:348-355.CrossrefPubMed Google Scholar

10 Han SH , LeeJK, KimHJ, et al.. The result of surgical treatment of medial epicondylitis: analysis with more than a 5-year follow-up. J Shoulder Elbow Surg2016;25:1704-1709.CrossrefPubMed Google Scholar

11 Kachooei AR , Talaei-KhoeiM, FaghfouriA, RingD. Factors associated with operative treatment of enthesopathy of the extensor carpi radialis brevis origin. J Shoulder Elbow Surg2016;25:666-670.CrossrefPubMed Google Scholar

12 Claessen FM , HeestersBA, ChanJJ, KachooeiAR, RingD. A meta-analysis of the effect of corticosteroid injection for enthesopathy of the extensor carpi radialis brevis origin. J Hand Surg Am2016;41:988-998.e2.CrossrefPubMed Google Scholar

13 Fabbri M , CiompiA, LanzettiRM, et al.. Muscle atrophy and fatty infiltration in rotator cuff tears: can surgery stop muscular degenerative changes?J Orthop Sci2016;21:614-618.CrossrefPubMed Google Scholar

14 Wilkerson J , ParyaviE, KimH, MurthiA, PensyRA. Biomechanical comparison of superior versus anterior plate position for fixation of distal clavicular fractures: a new model. J Orthop Trauma2016 (Epub ahead of print) PMID: 27661732.CrossrefPubMed Google Scholar

15 Kim JY , ChungSW, KimJH, et al.. A randomized trial among compression plus nonsteroidal antiinflammatory drugs, aspiration and aspiration with steroid injection for nonseptic olecranon bursitis. Clin Orthop Relat Res2016;474:776-783. Google Scholar