Abstract
Background
Autologous Chondrocyte Implantation (ACI) is frequently used to treat chondral defects in the knee with a good long-term outcome. This is contraindicatd in meniscal deficient knees. Allogenic Menicsal Transplantation (AMT) has been shown to give good symptomatic relief in meniscus deficient knees. However this is contraindicated in advanced cartilage degeneration. We hypothesized that combination of these two might be a solution for bone-on-bone arthritis in young individuals.
Methods
We studied a consecutive series of 12 patients who underwent combined ACI and AMT between 1998 and 2005. Pre operative and post operative comparisons of lysholm scores were recorded. Magnetic Resonance Imaging was performed to assess the integration ACI & AMT. Arthroscopy was performed at one year for assessment and obtain biopsy for histological examination.
Results
Out of the twelve patients only eleven were included as one had died at three months after surgery. The median pre-operative lysholm score was 45 which rose to 64 at one year. Magnetic Resonance Imaging showed good integration of both ACI and menisci. Most of the patients were able to lead an active lifestyle.
Conclusion
The combination of both ACI & AMT could give a good result and defer a total knee replacement in young indi
