Abstract
Introduction
Although total knee arthroplasty (TKA) in end-stage hemophilic arthropathy can reduce the severe joint pain and improve the functional disability, it is technically demanding. In addition, it has generally reported a high rate of complication including periprosthetic joint infection (PJI) and component loosening up to 20%. Although the Knee Society classification system of TKA complication was introduced, the complications of TKA in hemophilic arthropathy has not stratified using this classification system in previous articles to the best of our knowledge.
The purpose of this study was to evaluate the mid-term outcomes and complications of TKA in hemophilic arthropathy.
Methods
The study retrospectively reviewed 131 consecutive primary TKAs (102 patients) in single institute. The mean patient age was 41.0 years and mean follow-up time was 6.4 years. The clinical and radiographic results were evaluated. The complications were categorized according to the classification system of the Knee Society for TKA complications.
Results
The average WOMAC score improved from 66.0 to 24.2. The average flexion contracture significantly decreased from 17.3° to 4.7°, but the average pre and postoperative maximum flexion did not differ (80.9 ° vs. 85.6°). The average mechanical axis was varus 5.2° preoperatively and valgus 0.3° postoperatively. The coronal position of femoral and tibial components and sagittal position of those components were within ±3° in 83.2%, 89.3%, 63.4%, and 73.3%. The complications occurred in 17 knees (13.0%). There were 7 bleeding and hemarthrosis. Five knees were treated with increased amounts of coagulation factor concentrate and two knees were treated with incision and drainage of hematoma. One medial collateral ligament injury of grade 2 required change of postoperative rehabilitation protocol and bracing. Two stiffness of grade 3 required unplanned admission and manipulation under anesthesia. Three deep PJI were treated with 2 stage revision TKA. There were 4 periprosthetic fractures. Three distal femur fractures were treated with open reduction and internal fixation for 3 knees. One patellar fracture was healed with conservative treatment.
Conclusions
The mid-term results of TKA in end-stage hemophilic arthropathy were satisfactory with obtaining pain relief, improving function, and decreasing flexion contracture. Bleeding and PJI continues to be a major concern for TKA in patients with hemophilic arthropathy, and risk of periprosthetic fracture has to be taken into account for patient education and appropriate prevention.
Level of evidence
Level IV.
