EFFICACY OF PERI-ARTICULAR MULTIMODAL DRUG INFILTRATION IN TOTAL HIP REPLACEMENT

Abstract

Sixty four patients undergoing total hip replacement (THR) were randomized to receive a peri-articular intra-operative multi modal drug injection or to receive no injection. All patients received patient controlled analgesia (PCA) for 24 hours after surgery.

Patients receiving the peri-articular injection showed significantly less PCA consumption 6 hours postoperatively (P< 0.002). The 24 hour PCA requirement post surgery was also less (P< 0.009).

The VAS score for pain on activity in the post anaesthetic care unit (PACU) was significantly less for injected patients (P< 0.04). The VAS satisfaction score for injected patients in the PACU and 4 hours post-operatively showed no statistical difference.

Peri-articular intra-operative injection with multimodal drugs can significantly reduce post-operative patient controlled analgesia requirements and pain on activity in patients undergoing total hip replacement with no apparent increase in risk.