SYSTEMIC METAL LEVELS FOLLOWING REVISION OF FAILED RESURFACINGS TO CONVENTIONAL THRS.

Abstract

Introduction: source of elevated metal levels in patients with MM bearings continues to be debated. Under the controlled conditions of hip simulators most wear occurs within the first million cycles and subsequent motion produces negligible wear. However, in metal ion studies in patients, although there is a peak in metal levels in the early months after implantation, they never return to normal levels thereafter. In order to explain these conflicting observations it has been suggested that in vivo metal wear also occurs only during the early months and that continued corrosion of metal particles released during that period is responsible for metal level elevation later on.

If run-in wear is the only source of sustained metal release, then replacing the bearing with a non-MM bearing should not make a difference to metal release in patients and elevated levels should continue to persist even after such a revision. In order to verify this we studied metal release in patients who underwent revision of a MM bearing to a non-MM bearing after revision.

Methods. Using high resolution mass spectrometry, whole blood concentrations and daily output of cobalt and chromium were studied in four patients prospectively, whose hip resurfacings were revised to metal– polythylene THRs. None of the patients had other metal devices or compromised renal function.

Results. Preoperative levels in these patients were highly elevated as expected from a failing device. Thereafter there is a clear and progressively rapid trend of reducing metal levels in whole blood and urine.

Discussion The progressive and steep reduction of metal release following MM bearing removal suggests that corrosion from previously worn particles alone cannot account for the persistent elevation of systemic metal levels in patients with MM bearings and that bearing wear continues to occur after the initial run-in period