Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome

C. I. Leichtle; U. G. Leichtle; V. Gärtner; H. Schimmel; J. T. Hartmann; M. Rudert

doi:10.1302/0301-620X.88B3.16606

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Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome

C. I. Leichtle
U. G. Leichtle
V. Gärtner
H. Schimmel
J. T. Hartmann
M. Rudert

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Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome

Leichtle CI, Leichtle UG, Gärtner V, Schimmel H, Hartmann JT, Rudert M. Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome. J Bone Joint Surg Br. 2006;88-B(3):396-399. doi:10.1302/0301-620X.88B3.16606

Leichtle, C. I., et al. “Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome.” The Journal of Bone & Joint Surgery British Volume, vol. 88-B, no. 3, 2006, pp. 396-399., https://doi.org/10.1302/0301-620X.88B3.16606

Leichtle, C. I., Leichtle, U. G., Gärtner, V., Schimmel, H., Hartmann, J. T., & Rudert, M. (2006). Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome. The Journal of Bone & Joint Surgery British Volume, 88-B(3), 396-399. https://doi.org/10.1302/0301-620X.88B3.16606

Leichtle, C. I., Leichtle, U. G., Gärtner, V., Schimmel, H., Hartmann, J. T. and Rudert, M. (2006) “Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome.” The Journal of Bone & Joint Surgery British Volume, 88-B(3), pp. 396-399. Available at: https://doi.org/10.1302/0301-620X.88B3.16606

Leichtle, C. I., U. G. Leichtle, V. Gärtner, H. Schimmel, J. T. Hartmann, and M. Rudert. “Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome.” The Journal of Bone & Joint Surgery British Volume 88-B, no. 3 (2006): 396-399. https://doi.org/10.1302/0301-620X.88B3.16606

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Abstract

A giant cell tumour is a primary lesion of bone of intermediate severity. Its histogenesis is unclear. In a few cases pulmonary metastases have been described. Multiple skeletal metastases in the absence of sarcomatous change have been observed.

We present a case report of a 25-year-old woman with a recurrent giant cell tumour of the distal fibula. After a second recurrence and six years after the initial diagnosis, she rapidly developed multiple bony metastases. The outcome was fatal.

Correspondence should be sent to Dr M. Rudert; e-mail: maximilian.rudert@med.uni-tuebingen.de

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The Journal of Bone & Joint Surgery British Volume

Volume

88-B No.3 | Pages 396 - 399

Published

01 March 2006

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C. I. Leichtle

Orthopaedic Surgeon

Orthopaedic Department, Tübingen University Hospital, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.

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U. G. Leichtle

Orthopaedic Surgeon

Orthopaedic Department, Tübingen University Hospital, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.

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V. Gärtner

Pathologist, Professor

Institute of Pathology, Tübingen University Hospital, Liebermeisterstr. 8, D-72076 Tübingen, Germany.

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H. Schimmel

Pathologist

Institute of Pathology, Tübingen University Hospital, Liebermeisterstr. 8, D-72076 Tübingen, Germany.

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J. T. Hartmann

Internist, Specialist for Oncology

Department of Haematology, Oncology and Immunology Tübingen University Hospital, Ottfried-Müller-Str. 10, D-72076 Tübingen, Germany.

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M. Rudert

Orthopaedic Surgeon

Orthopaedic Department, Tübingen University Hospital, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.

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Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome

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