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THE IMPLICATIONS OF CHANGING THE TRANSFUSION TRIGGER FOR PRIMARY TOTAL KNEE ARTHROPLASTY



Abstract

Purpose: The objective of this study was to observe the change in transfusion rate by decreasing the transfusion trigger for patients undergoing primary total knee arthroplasty.

There are no transfusion guidelines defined for Total knee arthroplasty (TKA), and each orthopaedic unit usually has its own protocol when it comes to transfusion. With the present climate of concern about non-autologous blood transfusions and transmission of infection, orthopaedic units are trying to keep their transfusion rates to a minimum and only transfuse when absolutely necessary.

Method: The transfusion trigger prior to protocol change was a haematocrit (Hct) < 0.31, which was then changed to a lesser trigger of Hct < 0.25. We collected data on 331 patients; 181 patients prior to the change and 150 patients after the change. Each patient had undergone a primary TKA by a single surgeon using the same operative technique.

Results: In the group prior to change in transfusion trigger (Hct < 0.31), 76% of patients were transfused 88% of females and 54% of males. In this pre-trigger change group, 100% of patients with a pre-operative Hb of 12g/dl or less were transfused.

Of the 150 patients reviewed after the change in transfusion trigger (Hct < 0.25), only 29% were transfused – 35% of females and 18% of males. 50% of patients with a pre-operative Hb of 12 g/dl or less were transfused.

Conclusion: A change in the transfusion trigger greatly reduced the transfusion rate (reduction of 45%) with no adverse patient events. Obviously, this has both clinical and financial benefits. Pre-operative Hb is the best indicator as to whether a patient will require a transfusion following TKA. In order to decrease transfusion rates further, patients with a pre-operative Hb < 12 g/dl may benefit from pre-operative boosting of their Hb.

The abstracts were prepared by Emer Agnew. Correspondence should be addressed to Irish Orthopaedic Association, Secretariat, c/o Cappagh National Orthopaedic Hospital, Finglas, Dublin 11, Ireland.