O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES

Luca Proietti; G. Falcone; V. De Santis; F. Muratori; G. Maccauro

doi:10.1302/0301-620X.86BSUPP_III.0860256a

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O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES

Luca Proietti
G. Falcone
V. De Santis
F. Muratori
G. Maccauro

O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES

Proietti L, Falcone G, De Santis V, Muratori F, Maccauro G. O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES. Orthop Procs. 2004;86-B(SUPP_III):256-256. doi:10.1302/0301-620X.86BSUPP_III.0860256a

Proietti, Luca, et al. “O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES.” Orthopaedic Proceedings, vol. 86-B, no. SUPP_III, 2004, pp. 256-256., https://doi.org/10.1302/0301-620X.86BSUPP_III.0860256a

Proietti, L., Falcone, G., De Santis, V., Muratori, F., & Maccauro, G. (2004). O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES. Orthopaedic Proceedings, 86-B(SUPP_III), 256-256. https://doi.org/10.1302/0301-620X.86BSUPP_III.0860256a

Proietti, L., Falcone, G., De Santis, V., Muratori, F. and Maccauro, G. (2004) “O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES.” Orthopaedic Proceedings, 86-B(SUPP_III), pp. 256-256. Available at: https://doi.org/10.1302/0301-620X.86BSUPP_III.0860256a

Proietti, Luca, G. Falcone, V. De Santis, F. Muratori, and G. Maccauro. “O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES.” Orthopaedic Proceedings 86-B, no. SUPP_III (2004): 256-256. https://doi.org/10.1302/0301-620X.86BSUPP_III.0860256a

Proietti L, Falcone G, De Santis V, Muratori F, Maccauro G. O1292 NON-HODGKIN LYMPHOMA OF BONE. CLINICAL RESULTS ON A CONSECUTIVE SERIES OF 18 CASES. Orthop Procs. 2004 Mar 1;86-B(SUPP_III):256-256. https://doi.org/10.1302/0301-620X.86BSUPP_III.0860256a

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Abstract

Aims: Primary non-Hodgkin lymphoma of bone account for 5% of extra nodal lymphomas. The Authors report their experience referring to the results obtained with a multidisciplinary approach.

Materials: 18 cases of lymphoma of bone were included. Medium age was 63 yrs. All cases have been classified according to the REAL classification system. Patients have been staged with: total body CT scan, bone marrow aspirate, bone marrow biopsy, LDH serum level, skeletal survey and MRI of the skeletal segments involved. We treated 10 cases with solitary localization and 8 with multiple ones. Three patients presented with a pathologic fracture at diagnosis.

Chemotherapy protocols were:

MACOP-B < 60 yrs.

VNCOP-B > 60 yrs.

Seven patients received the PROMACE-CYTABOM protocol.

13 patients received EBRT (40 Gy). Ten patients received a surgical treatment: internal fixation in 7 cases and of spine stabilization in 3 cases

Results: At a medium follow-up of 40 months overall survival was 34,6 months and 14,5 months respectively for solitary or multiple localizations. Surgical treatment has been useful in improving performance status and in some cases to obtain a better control of the disease.

Discussion: In our experience bone lymphomas have always a high grade histology. Chemotherapy constitutes the treatment of choice. Surgical treatment have to be considered as a support treatment. Prognosis is worse in multiple localizations

Theses abstracts were prepared by Professor Dr. Frantz Langlais. Correspondence should be addressed to him at EFORT Central Office, Freihofstrasse 22, CH-8700 Küsnacht, Switzerland.