Abstract
Aim: To determine the histological changes in discs retrieved at the time of fusion following failed Intra-Discal Electrothermal Therapy (IDET).
Method: Three patients who had failed IDET treatment underwent lumbar interbody fusion. At the time of the operation the disc material and the endplate were sent for histopathology. The histological changes were compared to a degenerate disc and endplate. The staining techniques used were Haematoxylin Eosin stain, Elastic Van Geison and Alcian stains.
Results: In the post IDET specimens there was stromal disorganisation, paucity of chondrocytes and chondrocyte degeneration. These changes were seen in the nucleus pulposus, annulus fibrosis and the endplate as well. Comparatively cadaveric studies using intra-discal radiofrequency thermocoagulation showed histological change only in the nucleus pulposus.
Conclusion: The endplate changes at the cellular level can be widespread following IDET therapy, which can potentially cause alteration of its mechanical properties.
Abstracts prepared by Mr. A. J. Stirling, FRCS, and Miss A. Weaver. Correspondence should be addressed to Miss A. Weaver at the Research and Teaching Centre, Royal Orthopaedic Hospital, Northfield, Birmingham, B31 2AP, UK
BritSpine 2002, the second combined meeting of the British Association of Spinal Surgeons, the British Cervical Spine Society, The British Scoliosis Society and the Society for Back Pain Research, took place at the International Convention Centre in Birmingham UK between 27th February and 1st March 2002. The following presentations and posters were given and displayed.
